Multiview point cloud registration with anisotropic and space-varying localization noise
Denis Fortun, Etienne Baudrier, Fabian Zwettler, Markus Sauer, Sylvain Faisan

TL;DR
This paper presents a novel registration method for multiple point clouds corrupted with high anisotropic and space-varying noise, improving robustness by explicitly modeling the noise within a GMM-EM framework.
Contribution
It introduces an explicit anisotropic noise model into the GMM-EM registration framework, enabling handling of space-varying noise and leveraging prior noise knowledge.
Findings
Enhanced robustness to high anisotropic noise in simulations
Significant improvement over existing methods in real SMLM data
Effective handling of space-variant noise with closed-form EM solutions
Abstract
In this paper, we address the problem of registering multiple point clouds corrupted with high anisotropic localization noise. Our approach follows the widely used framework of Gaussian mixture model (GMM) reconstruction with an expectation-maximization (EM) algorithm. Existing methods are based on an implicit assumption of space-invariant isotropic Gaussian noise. However, this assumption is violated in practice in applications such as single molecule localization microscopy (SMLM). To address this issue, we propose to introduce an explicit localization noise model that decouples shape modeling with the GMM from noise handling. We design a stochastic EM algorithm that considers noise-free data as a latent variable, with closed-form solutions at each EM step. The first advantage of our approach is to handle space-variant and anisotropic Gaussian noise with arbitrary covariances. The…
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Taxonomy
TopicsMedical Imaging Techniques and Applications · Advanced Fluorescence Microscopy Techniques · Spectroscopy Techniques in Biomedical and Chemical Research
