On the Reception Process of Molecular Communication-Based Drug Delivery

TL;DR

This paper models the reception process in molecular communication-based drug delivery using queuing theory, providing bounds for drug dosage to minimize side effects and improve targeted delivery accuracy.

Contribution

It introduces a queuing theory-based model for drug molecule reception, accounting for rejection rates and establishing dosage bounds for safer, more effective targeted drug delivery.

Findings

Queuing theory effectively models drug molecule reception.

Rejection rates impact the optimal dosage range.

Proposed bounds help minimize side effects.

Abstract

One of the important applications of molecular communication is the targeted drug delivery process in which the drug molecules are released toward the target (receiver) in a way that the side effects are minimized in the human body. As the total number of released molecules increases, the receiver cannot receive all of the transmitted drug molecules. Therefore, the molecules would be accumulated in the system which results in side effects in the body. In order to diagnose the appropriate transmission rate of the drug molecules, it is important to investigate the reception process of the receiver. In this paper, a reception model is studied using queuing theory. In the proposed model, the rejection rate of the drug molecules due to different reasons, such as random movement of the molecules, as well as the rejection rate due to active receptors are taken into account. Moreover, an interval consisting of the lower and upper bounds for the number of released molecules is presented based on the proposed model in order to determine the range of allowable dosage of the drug molecules. It is shown that the queuing theory can be successfully employed in accurate modeling of the reception process of the receiver in drug delivery applications.