Full-volume three-component intraventricular vector flow mapping by triplane color Doppler

TL;DR

This paper introduces a novel 3D intraventricular vector flow mapping technique using triplane color Doppler, enabling comprehensive 3D blood flow visualization in the left ventricle with clinical applicability.

Contribution

The study generalizes 2D iVFM to 3D, allowing full-volume blood flow reconstruction in the ventricle using standard clinical echocardiography.

Findings

Validated in silico with CFD models

Demonstrated feasibility in vivo on volunteers

Captured intraventricular vortex dynamics during diastole

Abstract

Intraventricular vector flow mapping (iVFM) is a technique for retrieving 2-D velocity vector fields of blood flow in the left ventricle. This method is based on conventional color Doppler imaging, which makes iVFM compatible with the clinical setting. We have generalized the iVFM for a three-dimensional reconstruction (3D-iVFM). 3D-iVFM is able to recover three-component velocity vector fields in a full intraventricular volume by using a clinical echocardiographic triplane mode. As with the 2-D version, the method is based on the mass conservation, and free-slip boundary conditions on the endocardial wall. These mechanical constraints were imposed in a least-squares minimization problem that was solved through the method of Lagrange multipliers. We validated 3D-iVFM in silico in a patient-specific CFD (computational fluid dynamics) model of cardiac flow, and tested its feasibility in vivo on volunteers. In both in silico and in vivo investigations, the dynamics of the intraventricular vortex that forms during diastole was deciphered by 3D-iVFM. Our results tend to indicate that 3D-iVFM could provide full-volume echocardiographic information on left intraventricular hemodynamics from the clinical modality of triplane color Doppler.