Well-posedness of an integro-differential model for active Brownian particles
Maria Bruna, Martin Burger, Antonio Esposito, Simon Schulz

TL;DR
This paper establishes the well-posedness of a nonlinear integro-differential model for active Brownian particles, providing a rigorous mathematical foundation for analyzing such systems with nonlocal interactions and low-regularity initial data.
Contribution
It introduces a novel existence and uniqueness proof for a class of nonlinear integro-differential equations modeling active Brownian particles, including cases with distributional initial data.
Findings
Proved global existence and uniqueness of weak solutions.
Extended well-posedness to very weak initial data.
Included finite systems with a finite number of directions.
Abstract
We propose a general strategy for solving nonlinear integro-differential evolution problems with periodic boundary conditions, where no direct maximum/minimum principle is available. This is motivated by the study of recent macroscopic models for active Brownian particles with repulsive interactions, consisting of advection-diffusion processes in the space of particle position and orientation. We focus on one of such models, namely a semilinear parabolic equation with a nonlinear active drift term, whereby the velocity depends on the particle orientation and angle-independent overall particle density (leading to a nonlocal term by integrating out the angular variable). The main idea of the existence analysis is to exploit a-priori estimates from (approximate) entropy dissipation. The global existence and uniqueness of weak solutions is shown using a two-step Galerkin approximation with…
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Taxonomy
TopicsMathematical Biology Tumor Growth · Stochastic processes and statistical mechanics · Stochastic processes and financial applications
