ProLiVis: Protein-Protein Interaction Literature Visualization System

TL;DR

ProLiVis is a visualization system for Protein-Protein Interactions that integrates literature and methods, offering a comprehensive, multi-level view of PPI networks across organisms, enhancing understanding beyond existing tools.

Contribution

It introduces a novel three-level visualization model that combines literature, methods, and interactions, improving over current tools by providing a holistic view of PPI data.

Findings

Supports visualization of all interactions for selected organisms

Abstracts networks based on experimental methods and publication ownership

More efficient than parsing text files or databases

Abstract

We provide a visualization model that targets the visualization of Protein-Protein Interactions(PPI) and combines it with a super view based on publications and methods to extract interactions. Although there are several existing tools, our model considers the existing literature and is capable to demonstrate all interactions for the selected organisms. In our model, we propose a three-level visualization concept for the PPI networks with the current state-of-the-art studies based on several organisms. And, we abstract of overall network based on two perspectives; "experimental method types of each interaction" and "ownership with the publication". We claim that it is more efficient to work on our proposed layout rather than parsing text files or databases. For that way, we plan to support the existing visuals with complementary outsourced information from the existing knowledge base.