Constrained Deep One-Class Feature Learning For Classifying Imbalanced Medical Images

TL;DR

This paper introduces a deep learning method that combines constrained feature learning and autoencoder training to improve classification of imbalanced medical images, achieving state-of-the-art results.

Contribution

It proposes a novel joint optimization approach that enhances feature relevance for one-class classification in imbalanced medical imaging datasets.

Findings

Achieved state-of-the-art performance on three clinical datasets.

Effectively distinguishes minority and majority classes.

Improves feature relevance for imbalanced data classification.

Abstract

Medical image data are usually imbalanced across different classes. One-class classification has attracted increasing attention to address the data imbalance problem by distinguishing the samples of the minority class from the majority class. Previous methods generally aim to either learn a new feature space to map training samples together or to fit training samples by autoencoder-like models. These methods mainly focus on capturing either compact or descriptive features, where the information of the samples of a given one class is not sufficiently utilized. In this paper, we propose a novel deep learning-based method to learn compact features by adding constraints on the bottleneck features, and to preserve descriptive features by training an autoencoder at the same time. Through jointly optimizing the constraining loss and the autoencoder's reconstruction loss, our method can learn more relevant features associated with the given class, making the majority and minority samples more distinguishable. Experimental results on three clinical datasets (including the MRI breast images, FFDM breast images and chest X-ray images) obtains state-of-art performance compared to previous methods.