Chitosan Nanocomposites with CdSe/ZnS Quantum Dots and Porphyrin
F. A. Sewid, K. I. Annas, A. Dubavik, A. V. Veniaminov, V.G. Maslov,, A. O.Orlov
TL;DR
This study develops water-soluble chitosan-based nanocomposites incorporating CdSe/ZnS quantum dots and porphyrin, demonstrating enhanced singlet oxygen generation through energy transfer, with potential applications in photodynamic therapy.
Contribution
It introduces a novel water-soluble nanocomposite combining quantum dots and porphyrin with improved singlet oxygen production via FRET.
Findings
Enhanced singlet oxygen generation compared to free TPP.
Successful formation of stable, water-soluble nanocomposites.
Evidence of intracomplex FRET with 45% efficiency.
Abstract
Water-soluble nanocomposites based on CdSe/ZnS quantum dots (QDs) and hydrophobic tetraphenylporphyrin (TPP) molecules passivated by chitosan (CS) have been formed. Magnetic circular dichroism (MCD) spectra evidence TPP presence in both monomeric and agglomerated forms in the nanocomposites. The nanocomposites demonstrate more pronounced singlet oxygen generation in comparison with free TPP in CS at the same concentration due to intracomplex Forster resonance energy transfer (FRET) with 45 % average efficiency.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsPorphyrin and Phthalocyanine Chemistry · Photosynthetic Processes and Mechanisms · Protein Interaction Studies and Fluorescence Analysis