Active information requirements for fixation on the Wright-Fisher model of population genetics

TL;DR

This paper extends the concept of active information to population genetics, illustrating how information changes from neutral to non-neutral models like Wright-Fisher, which include selection and mutation effects.

Contribution

It introduces the application of active information to the Wright-Fisher model, highlighting how information measures evolve with non-neutral influences in population genetics.

Findings

Active information quantifies the shift from neutral to non-neutral models.

Illustrates the impact of selection and mutation on allele fixation.

Provides a framework for measuring information change in genetic models.

Abstract

In the context of population genetics, active information can be extended to measure the change of information of a given event (e.g., fixation of an allele) from a neutral model in which only genetic drift is taken into account to a non-neutral model that includes other sources of frequency variation (e.g., selection and mutation). In this paper we illustrate active information in population genetics through the Wright-Fisher model.