Photo-acoustic inversion using plasmonic contrast agents: The full Maxwell model

TL;DR

This paper develops a full Maxwell model for photo-acoustic inversion using plasmonic contrast agents, enabling the reconstruction of complex permittivity from single-point pressure measurements across frequencies.

Contribution

It introduces a novel inversion method based on the full Maxwell system and spectral analysis, providing new insights into plasmonic resonance detection and permittivity reconstruction.

Findings

Pressure measurements can reconstruct complex permittivity.

Indicator functions peak near plasmonic resonances.

Electric field analysis justifies the inversion approach.

Abstract

We analyze the inversion of the photo-acoustic imaging modality using electromagnetic plasmonic nano-particles as contrast agents. We prove that the generated pressure, before and after injecting the plasmonic nano-particles, measured at a single point, located away from the targeted inhomogeneity to image, and at a given band of incident frequencies is enough to reconstruct the (eventually complex valued) permittivity. Indeed, from these measurements, we define an indicator function which depends on the used incident frequency and the time of measurement. This indicator function has differentiating behaviors in terms of both time and frequency. First, from the behavior in terms of time, we can estimate the arrival time of the pressure from which we can localize the injected nano-particle. Second, we show that this indicator function has maximum picks at incident frequencies close to the plasmonic resonances. This allows us to estimate these resonances from which we construct the permittivity. To justify these properties, we derive the dominant electric field created by the injected nano-particle when the incident frequency is close to plasmonic resonances. This is done for the full Maxwell system. To this end, we use a natural spectral decomposition of the vector space (L^2(D))^3 based on the spectra of the Newtonian and the Magnetization operators. As another key argument, we provide the singularity analysis of the Green's tensor of the Maxwell problem with varying permittivity. Such singularity is unusual if compared to the ones of the elliptic case (as the acoustic or elastic models). In addition, we show how the derived approximation of the electric fields propagates, as a source, in the induced pressure with the time.