Process Design and Economics of Production of p-Aminophenol

TL;DR

This paper presents a detailed business plan and simulation for establishing a Para-Aminophenol production plant in India, addressing supply security and economic viability amidst import dependence.

Contribution

It introduces a comprehensive process design and economic analysis for a new Indian Para-Aminophenol manufacturing plant using AspenPlus simulation.

Findings

Plant produces 22.7 kmols/hr with 99.9% purity

Economic analysis includes Payback Period and ROI calculations

Simulation validates process feasibility and cost-effectiveness

Abstract

Para-Aminophenol is one of the key chemicals required for the synthesis of Paracetamol, an analgesic and antipyretic drug. Data shows a large fraction of India's demand for Para-Aminophenol being met through imports from China. The uncertainty in the India-China relations would affect the supply and price of this "Key Starting Material." This report is a detailed business plan for setting up a plant and producing Para-Aminophenol in India at a competitive price. The plant is simulated in AspenPlus V8 and different Material Balances and Energy Balances calculations are carried out. The plant produces 22.7 kmols Para-Aminophenol per hour with a purity of 99.9%. Along with the simulation, economic analysis is carried out for this plant to determine the financial parameters like Payback Period and Return on Investment.