
TL;DR
This paper examines the dual effects of mass vaccination during an ongoing pandemic, highlighting its role in reducing virus spread while potentially driving the emergence of resistant strains.
Contribution
It provides an analysis of the balance between vaccination benefits and evolutionary pressures during active epidemics.
Findings
Vaccination reduces virus circulation effectively.
Mass vaccination can induce resistant strains.
Timing of vaccination impacts evolutionary dynamics.
Abstract
Mass vaccination produces a reduction in virus circulation, but also evolutive pressure towards the appearance of virus-resistant strains. We discuss the balance between these two effects, in particular when the mass vaccination takes place in the middle of an epidemic period.
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