Cross-time functional connectivity analysis

TL;DR

This paper introduces a novel method for analyzing cross-time inter-regional functional connectivity in the mammal brain, extending temporal coherence analysis to characterize dynamic interareal interactions.

Contribution

It develops a new tool for cross-time functional connectivity analysis based on temporal embedding, validated with synthetic and in-vivo data.

Findings

Effective characterization of cross-time inter-regional connectivity

Validated method with synthetic and real data

Provides insights into dynamic brain interactions

Abstract

A large body of literature has shown the substantial inter-regional functional connectivity in the mammal brain. One important property remaining un-studied is the cross-time interareal connection. This paper serves to provide a tool to characterize the cross-time functional connectivity. The method is extended from the temporal embedding based brain temporal coherence analysis. Both synthetic data and in-vivo data were used to evaluate the various properties of the cross-time functional connectivity matrix, which is also called the cross-regional temporal coherence matrix.