Optical phased array neural probes for beam-steering in brain tissue
Wesley D. Sacher, Fu-Der Chen, Homeira Moradi-Chameh, Xinyu Liu, Ilan, Felts Almog, Thomas Lordello, Michael Chang, Azadeh Naderian, Trevor M., Fowler, Eran Segev, Tianyuan Xue, Sara Mahallati, Taufik A. Valiante, Laurent, C. Moreaux, Joyce K. S. Poon, and Michael L. Roukes
TL;DR
This paper presents implantable neural probes with integrated optical phased arrays that enable dynamic beam steering for optogenetics and calcium imaging in brain tissue, combining nanophotonics and neural interfaces.
Contribution
Introduction of neural probes with integrated optical phased arrays for in vivo beam steering and neural modulation in brain tissue.
Findings
Successful in vitro beam steering demonstration
Effective optogenetic stimulation and calcium imaging
Simulated and characterized beam formation in tissue
Abstract
Implantable silicon neural probes with integrated nanophotonic waveguides can deliver patterned dynamic illumination into brain tissue at depth. Here, we introduce neural probes with integrated optical phased arrays and demonstrate optical beam steering in vitro. Beam formation in brain tissue was simulated and characterized. The probes were used for optogenetic stimulation and calcium imaging.
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