Known Operator Learning and Hybrid Machine Learning in Medical Imaging -- A Review of the Past, the Present, and the Future
Andreas Maier, Harald K\"ostler, Marco Heisig, Patrick Krauss, Seung, Hee Yang

TL;DR
This review discusses the evolution, current trends, and future prospects of hybrid machine learning in medical imaging, emphasizing known operator learning and its expanding role across various applications.
Contribution
It provides a comprehensive overview of hybrid machine learning developments, focusing on known operator learning and its increasing adoption in medical image reconstruction and analysis.
Findings
Hybrid models are increasingly used in image reconstruction and analysis.
Hybrid approaches are applied in physical simulation and scanner design.
Future directions include hybrid modeling, meta learning, and other advanced techniques.
Abstract
In this article, we perform a review of the state-of-the-art of hybrid machine learning in medical imaging. We start with a short summary of the general developments of the past in machine learning and how general and specialized approaches have been in competition in the past decades. A particular focus will be the theoretical and experimental evidence pro and contra hybrid modelling. Next, we inspect several new developments regarding hybrid machine learning with a particular focus on so-called known operator learning and how hybrid approaches gain more and more momentum across essentially all applications in medical imaging and medical image analysis. As we will point out by numerous examples, hybrid models are taking over in image reconstruction and analysis. Even domains such as physical simulation and scanner and acquisition design are being addressed using machine learning grey…
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