Cell mechanics and signalisation: SARS-CoV-2 hijacks membrane liquid crystals and cytoskeletal fractal topology
Christiane Binot, Jean-Francois Sadoc, Claude-Henri Chouard
TL;DR
This paper explores how SARS-CoV-2 hijacks cell membrane liquid crystals and fractal cytoskeletal structures, disrupting cell signaling and membrane mechanics during viral invasion.
Contribution
It reveals the mechanisms by which the virus alters membrane properties and nanodomain organization through cytoskeletal fractal topology.
Findings
Virus impairs membrane mesophase structures
Disruption of fractal cytoskeletal architecture
Altered mechanical properties of cell membranes
Abstract
We highlight changes to cell signalling under virus invasion (SARS-CoV-2), involving disturbance of membranes and of nanodomains, modulated by the cytoskeleton. Virus alters the mechanical properties of the membranes, impairing mesophase structures mediated by the fractal architecture initiated by actomyosin.
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Taxonomy
TopicsErythrocyte Function and Pathophysiology · Lipid Membrane Structure and Behavior