Continuous Wave Multipass Microscopy

TL;DR

This paper introduces a continuous-wave, multipass microscopy technique that enhances imaging signals by interrogating samples multiple times without complex detection, improving image quality with simple, incoherent light sources.

Contribution

The work presents a novel, post selection-free multipass microscopy method capable of up to four sequential interrogations, increasing signal strength without complex detection schemes.

Findings

Deterministic multiple interrogations up to four times

Linear enhancement in phase shift and absorption signals

Improved signal-to-noise ratio in widefield microscopy

Abstract

We present a continuous-wave, post selection-free implementation of a widefield optical multipass microscope. It can be operated with a spatially and temporally incoherent light source, and requires no active outcoupling or exotic detection schemes. This implementation is capable of deterministically interrogating a sample sequentially up to $m=4$ times. Through multiple interrogations, a linear enhancement in phase shift and absorption imparted by the sample can be achieved, fundamentally increasing the signal-to-noise of the obtainable images.