Two-Stage Self-Supervised Cycle-Consistency Network for Reconstruction of Thin-Slice MR Images

TL;DR

This paper introduces a novel two-stage self-supervised cycle-consistency network (TSCNet) for reconstructing high-resolution thin-slice MR images from low-resolution images, addressing the challenge of limited paired data and improving interpolation quality.

Contribution

The paper proposes a two-stage self-supervised learning strategy with cycle-consistency constraints for MR image slice interpolation, enabling effective training without paired data.

Findings

TSCNet outperforms conventional and SSL-based algorithms in experiments.

Achieves results comparable to fully supervised methods.

Utilizes cyclic interpolation and cycle-consistency for improved image quality.

Abstract

The thick-slice magnetic resonance (MR) images are often structurally blurred in coronal and sagittal views, which causes harm to diagnosis and image post-processing. Deep learning (DL) has shown great potential to re-construct the high-resolution (HR) thin-slice MR images from those low-resolution (LR) cases, which we refer to as the slice interpolation task in this work. However, since it is generally difficult to sample abundant paired LR-HR MR images, the classical fully supervised DL-based models cannot be effectively trained to get robust performance. To this end, we propose a novel Two-stage Self-supervised Cycle-consistency Network (TSCNet) for MR slice interpolation, in which a two-stage self-supervised learning (SSL) strategy is developed for unsupervised DL network training. The paired LR-HR images are synthesized along the sagittal and coronal directions of input LR images for network pretraining in the first-stage SSL, and then a cyclic in-terpolation procedure based on triplet axial slices is designed in the second-stage SSL for further refinement. More training samples with rich contexts along all directions are exploited as guidance to guarantee the improved in-terpolation performance. Moreover, a new cycle-consistency constraint is proposed to supervise this cyclic procedure, which encourages the network to reconstruct more realistic HR images. The experimental results on a real MRI dataset indicate that TSCNet achieves superior performance over the conventional and other SSL-based algorithms, and obtains competitive quali-tative and quantitative results compared with the fully supervised algorithm.