Maximum profile binomial likelihood estimation for the semiparametric Box--Cox power transformation model
Pengfei Li, Tao Yu, Baojiang Chen, and Jing Qin

TL;DR
This paper introduces a new semiparametric estimation method for the Box--Cox transformation model that is robust to unknown error distributions and performs well compared to existing techniques.
Contribution
The paper proposes a maximum profile binomial likelihood approach for the semiparametric Box--Cox model, with theoretical distribution results and superior empirical performance.
Findings
Method outperforms existing methods when error distribution deviates from normal.
Theoretical joint distribution of estimators is established.
Demonstrated effectiveness on HIV data set.
Abstract
The Box--Cox transformation model has been widely applied for many years. The parametric version of this model assumes that the random error follows a parametric distribution, say the normal distribution, and estimates the model parameters using the maximum likelihood method. The semiparametric version assumes that the distribution of the random error is completely unknown; existing methods either need strong assumptions, or are less effective when the distribution of the random error significantly deviates from the normal distribution. We adopt the semiparametric assumption and propose a maximum profile binomial likelihood method. We theoretically establish the joint distribution of the estimators of the model parameters. Through extensive numerical studies, we demonstrate that our method has an advantage over existing methods, especially when the distribution of the random error…
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsHIV Research and Treatment · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions
