Multidimensional Scaling for Gene Sequence Data with Autoencoders
Pulasthi Wickramasinghe, Geoffrey Fox

TL;DR
This paper introduces an autoencoder-based dimensionality reduction model for gene sequence data that scales efficiently to large datasets and achieves high accuracy, comparable to traditional MDS methods.
Contribution
The paper presents a novel autoencoder-based model for multidimensional scaling of gene sequences that is scalable and resource-efficient, outperforming existing algorithms in large datasets.
Findings
Scales to millions of gene sequences with minimal resources
Achieves over 99.5% accuracy on out-of-sample data
Comparable results to state-of-the-art MDS algorithms
Abstract
Multidimensional scaling of gene sequence data has long played a vital role in analysing gene sequence data to identify clusters and patterns. However the computation complexities and memory requirements of state-of-the-art dimensional scaling algorithms make it infeasible to scale to large datasets. In this paper we present an autoencoder-based dimensional reduction model which can easily scale to datasets containing millions of gene sequences, while attaining results comparable to state-of-the-art MDS algorithms with minimal resource requirements. The model also supports out-of-sample data points with a 99.5%+ accuracy based on our experiments. The proposed model is evaluated against DAMDS with a real world fungi gene sequence dataset. The presented results showcase the effectiveness of the autoencoder-based dimension reduction model and its advantages.
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