Specific loss power of magnetic nanoparticles (fluid) hyperthermia in non-adiabatic conditions

TL;DR

This paper presents a thermodynamic approach to magnetic hyperthermia in non-adiabatic conditions, improving the accuracy of specific loss power estimation and clarifying previously misunderstood parameters through experiments with magnetic nanoparticles.

Contribution

It introduces a new thermodynamic model for magnetic hyperthermia in non-adiabatic conditions and validates it with experimental data, providing physical insights into key parameters.

Findings

Enhanced accuracy in specific loss power estimation.

Physical interpretation of previously unclear parameters.

Experimental validation with magnetite and magnesium ferrite nanoparticles.

Abstract

We investigate the magnetic nanoparticles (fluid) hyperthermia in non-adiabatic conditions through the calorimetric method. Specifically, we propose a theoretical approach to magnetic hyperthermia from a thermodynamic point of view. To test the robustness of the approach, we perform hyperthermia experiments and analyze the thermal behavior of magnetite and magnesium ferrite magnetic nanoparticles dispersed in water submitted to an alternating magnetic field. From our findings, besides estimating the specific loss power value from a non-adiabatic process, thus enhancing the accuracy in the determination of this quantity, we provide physical meaning to parameters found in literature that still remained not fully understood, and bring to light how they can be obtained experimentally.