Multi-phase Deformable Registration for Time-dependent Abdominal Organ Variations

TL;DR

This paper introduces a fast and precise deformable registration algorithm for multi-phase abdominal CT scans that accounts for complex organ motions, improving alignment accuracy for medical imaging analysis.

Contribution

It presents a novel registration method capable of handling differentiable and non-differentiable organ motions in abdominal CT scans, achieving high accuracy within one minute.

Findings

Registration accuracy of 0.85mm for pancreas

Achieves fast processing within 1 minute

Effective for complex multi-phase abdominal motions

Abstract

Human body is a complex dynamic system composed of various sub-dynamic parts. Especially, thoracic and abdominal organs have complex internal shape variations with different frequencies by various reasons such as respiration with fast motion and peristalsis with slower motion. CT protocols for abdominal lesions are multi-phase scans for various tumor detection to use different vascular contrast, however, they are not aligned well enough to visually check the same area. In this paper, we propose a time-efficient and accurate deformable registration algorithm for multi-phase CT scans considering abdominal organ motions, which can be applied for differentiable or non-differentiable motions of abdominal organs. Experimental results shows the registration accuracy as 0.85 +/- 0.45mm (mean +/- STD) for pancreas within 1 minute for the whole abdominal region.