Update on the multimodal pathophysiological dataset of gradual cerebral ischemia in a cohort of juvenile pigs: auditory, sensory and high-frequency sensory evoked potentials

TL;DR

This paper presents an expanded multimodal dataset of brain electrical activities in juvenile pigs, including evoked potentials under various conditions, enabling better understanding of corticothalamic communication and aiding development of brain monitoring tools.

Contribution

The study introduces a comprehensive, validated dataset of evoked potentials in juvenile pigs across different states, combining spontaneous and evoked activities for advanced neurological research.

Findings

Validated evoked responses during sedation, ischemia, and recovery.

Dataset includes auditory, sensory, and high-frequency oscillation potentials.

Facilitates future research on brain monitoring and injury prevention.

Abstract

We expand from a spontaneous to an evoked potentials (EP) data set of brain electrical activities as electrocorticogram (ECoG) and electrothalamogram (EThG) in juvenile pig under various sedation, ischemia and recovery states. This EP data set includes three stimulation paradigms: auditory (AEP, 40 and 2000 Hz), sensory (SEP, left and right maxillary nerve) and high-frequency oscillations (HFO) SEP. This permits derivation of electroencephalogram (EEG) biomarkers of corticothalamic communication under these conditions. The data set is presented in full band sampled at 2000 Hz. We provide technical validation of the evoked responses for the states of sedation, ischemia and recovery. This extended data set now permits mutual inferences between spontaneous and evoked activities across the recorded modalities. Future studies on the dataset may contribute to the development of new brain monitoring technologies, which will facilitate the prevention of neurological injuries.