Zero-Shot Self-Supervised Learning for MRI Reconstruction

TL;DR

This paper introduces a zero-shot self-supervised learning method for MRI reconstruction that enables high-quality, subject-specific results without relying on external training data, addressing generalization and data availability issues.

Contribution

The work presents a novel zero-shot self-supervised approach for MRI reconstruction that does not require external datasets and can incorporate transfer learning for efficiency.

Findings

Effective subject-specific MRI reconstruction without external data

Combines self-supervision with data partitioning for validation

Transfer learning accelerates convergence and reduces complexity

Abstract

Deep learning (DL) has emerged as a powerful tool for accelerated MRI reconstruction, but often necessitates a database of fully-sampled measurements for training. Recent self-supervised and unsupervised learning approaches enable training without fully-sampled data. However, a database of undersampled measurements may not be available in many scenarios, especially for scans involving contrast or translational acquisitions in development. Moreover, recent studies show that database-trained models may not generalize well when the unseen measurements differ in terms of sampling pattern, acceleration rate, SNR, image contrast, and anatomy. Such challenges necessitate a new methodology to enable subject-specific DL MRI reconstruction without external training datasets, since it is clinically imperative to provide high-quality reconstructions that can be used to identify lesions/disease for \emph{every individual}. In this work, we propose a zero-shot self-supervised learning approach to perform subject-specific accelerated DL MRI reconstruction to tackle these issues. The proposed approach partitions the available measurements from a single scan into three disjoint sets. Two of these sets are used to enforce data consistency and define loss during training for self-supervision, while the last set serves to self-validate, establishing an early stopping criterion. In the presence of models pre-trained on a database with different image characteristics, we show that the proposed approach can be combined with transfer learning for faster convergence time and reduced computational complexity. The code is available at \url{https://github.com/byaman14/ZS-SSL}.