A General Model of Structured Cell Kinetics
Michael Grinfeld, Nigel Mottram, Jozsef Farkas
TL;DR
This paper introduces a comprehensive mathematical framework to model the dynamics of cell populations structured by intracellular molecule concentrations, applicable to various biological processes.
Contribution
It develops general equations for cell population and molecule concentration evolution, extending modeling capabilities across different biological systems.
Findings
Unified modeling framework for structured cell kinetics
Application to silicosis, quorum sensing, and magnetic ion exchange models
Derivation of general equations for cell and molecule dynamics
Abstract
We present a modelling framework for the dynamics of cells structured by the concentration of a micromolecule they contain. We derive general equations for the evolution of the cell population and of the extra-cellular concentration of the molecule and apply this approach to models of silicosis, quorum sensing in Gram-negative bacteria and magnetic ion exchange.
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Taxonomy
TopicsBacterial biofilms and quorum sensing · Bacteriophages and microbial interactions · Bacterial Genetics and Biotechnology