Brain Modelling as a Service: The Virtual Brain on EBRAINS

TL;DR

The Virtual Brain platform on EBRAINS provides an open-source cloud environment for constructing, simulating, and analyzing brain network models, supporting collaborative research and clinical applications in brain science.

Contribution

It introduces a comprehensive cloud-based ecosystem for brain modeling, simulation, and analysis, integrating diverse tools and data for scalable neuroscience research.

Findings

Enables reproducible online collaboration.

Supports simulation of patient-specific brain models.

Facilitates research on large cohort datasets.

Abstract

The Virtual Brain (TVB) is now available as open-source cloud ecosystem on EBRAINS, a shared digital research platform for brain science. It offers services for constructing, simulating and analysing brain network models (BNMs) including the TVB network simulator; magnetic resonance imaging (MRI) processing pipelines to extract structural and functional connectomes; multiscale co-simulation of spiking and large-scale networks; a domain specific language for automatic high-performance code generation from user-specified models; simulation-ready BNMs of patients and healthy volunteers; Bayesian inference of epilepsy spread; data and code for mouse brain simulation; and extensive educational material. TVB cloud services facilitate reproducible online collaboration and discovery of data assets, models, and software embedded in scalable and secure workflows, a precondition for research on large cohort data sets, better generalizability and clinical translation.