The Gossip Paradox: why do bacteria share genes?

TL;DR

This paper explores the paradox of bacterial gene sharing, showing through models and simulations that bacteria tend to share genes despite potential costs, revealing complex evolutionary dynamics.

Contribution

It introduces models demonstrating that secretive genes are favored, explaining why bacteria share genes despite apparent disadvantages.

Findings

Secretive genes are favored over wide models and parameters.

Bacteria share genes despite potential costs, indicating complex evolutionary benefits.

The paradox challenges assumptions about bacterial cooperation and competition.

Abstract

Bacteria, in contrast to eukaryotic cells contain two types of genes: chromosomal genes that are fixed to the cell, and plasmids that are mobile genes, easily shared to other cells. The sharing of plasmid genes between individual bacteria and between bacterial lineages has contributed vastly to bacterial evolution, allowing specialized traits to `jump ship' between one lineage or species and the next. The benefits of this generosity from the point of view of both recipient and plasmid are generally understood, but come at the expense of chromosomal genes in the donor cell, which share potentially advantageous genes with their competition while receiving no benefit. Using both continuous models and agent based simulations, we demonstrate that `secretive' genes which restrict horizontal gene transfer are favored over wide range of models and parameter values. Our findings lead to a peculiar paradox: given the obvious benefits of keeping secrets, why do bacteria share information so freely?