Unified k-space theory of optical coherence tomography

TL;DR

This paper introduces a comprehensive 3D k-space framework for optical coherence tomography (OCT), unifying various OCT techniques and explaining fundamental physical phenomena in the field.

Contribution

It presents a novel 3D k-space formalism that unifies multiple OCT methods and explains core physical properties, advancing the theoretical understanding of OCT.

Findings

Unified 3D k-space framework for OCT

Explains contrast, resolution, dispersion, and aberration in OCT

Links various OCT techniques under a common theory

Abstract

We present a general theory of optical coherence tomography (OCT), which synthesizes the fundamental concepts and implementations of OCT under a common 3D k-space framework. At the heart of this analysis is the Fourier diffraction theorem, which relates the coherent interaction between a sample and plane wave to the Ewald sphere in the 3D k-space representation of the sample. While only the axial dimension of OCT is typically analyzed in k-space, we show that embracing a fully 3D k-space formalism allows explanation of nearly every fundamental physical phenomenon or property of OCT, including contrast mechanism, resolution, dispersion, aberration, limited depth of focus, and speckle. The theory also unifies diffraction tomography, confocal microscopy, point-scanning OCT, line-field OCT, full-field OCT, Bessel-beam OCT, transillumination OCT, interferometric synthetic aperture microscopy (ISAM), and optical coherence refraction tomography (OCRT), among others. Our unified theory not only enables clear understanding of existing techniques, but also suggests new research directions to continue advancing the field of OCT.