Terahertz resonance response of biological tissue placed on a silicon nanostructure

TL;DR

This paper introduces a method to measure the terahertz resonance response of biological tissues on silicon nanostructures, potentially enabling rapid medical diagnosis of diseases like cancer.

Contribution

It demonstrates a novel technique using silicon nanosandwich devices to detect THz responses in living tissues, advancing biomedical sensing capabilities.

Findings

THz resonance response can be generated in living biotissue

The SNS device detects changes in conductance and voltage related to tissue properties

Potential application in rapid medical diagnosis of oncological diseases

Abstract

We present a method for the measurements of the tetrahertz (THz) resonance response of DNA oligonucleotides deposited on a silicon nanosandwich (SNS). It is shown that the SNS device can be used to generate a THz resonance response within living biotissue. The technique we propose measures changes of the longitudinal conductance and the lateral voltage with the SNS device in a Hall geometry. The mechanism of the THz response is discussed, with a model of the generation of Shapiro steps. The THz resonance response from living biotissues will aid the diagnosis of oncological disease and, in general, form the basis of a rapid diagnosis in practical medicine.