Porous Structured Au Colloids: Insights in to Morphology, Optical and Antimicrobial Activity

TL;DR

This study synthesizes porous structured gold colloids from bulk nanoporous gold, analyzing their morphology, optical properties, and antimicrobial activity, revealing their potential for biomedical applications.

Contribution

It introduces a novel method to prepare porous structured Au colloids and comprehensively characterizes their enhanced optical and antimicrobial properties.

Findings

Porous Au colloids exhibit two plasmon resonance peaks at 477 and 546 nm.

SEM and AFM show rod-shaped morphology with skeletal pore structures.

Porous Au colloids demonstrate significant antimicrobial activity against bacteria.

Abstract

Porous structured Au colloids have been prepared from bulk nanoporous Au by means of an element dissociation method. The microscopic techniques (scanning electron microscope and atomic force microscope), UV-Vis spectroscopy and zone diffusion method have been employed to study their morphology, optical property and anti-microbial activity against Gram-positive and Gram-negative bacterial strains, respectively. It is shown that the porous structured Au colloidal suspension exhibit excellent optical and antimicrobial properties. The noticeable features present in the optical studies are two Plasmon resonance peaks at 477 and 546 nm with overlapping of these peaks at a wavelength of 520 nm. The morphology studies by SEM and AFM indicate that the Au colloids are rod shaped with an assembly of skeletal pore and ligament structure. The analysis of the antimicrobial activity testing reveals that the porous structured Au colloids have greater inhibitory effect against the tested Gram-positive and Gram-negative bacterial strains.