Experimental analysis of a Multilayer Flow Modulator deployment in an AAA with incorporated branch

TL;DR

This experimental study evaluates a Multilayer Flow Modulator's impact on flow dynamics in an AAA model, demonstrating its ability to reduce aneurysm flow velocity while preserving branch flow, informing safer endovascular treatments.

Contribution

The paper provides the first experimental analysis of MFM deployment in AAA with an incorporated branch, highlighting its effects on flow patterns and device safety.

Findings

Aneurysm flow velocity was significantly reduced.

Flow rate of the incorporated branch was preserved.

Flow patterns were modified to reduce vorticity.

Abstract

Purpose: To experimentally evaluate the effect of a Multilayer Flow Modulator (MFM) device deployment in an Abdominal Aortic Aneurysm (AAA) model with and without incorporated branch. Methods: An experimental flow and pressure monitoring system was developed to analyze the MFM deployment procedure performed by a qualified radiologist. The pressure and flow rate evolution during the procedure was recorded. Particle Image Velocimetry (PIV) experiments were conducted on models with and without MFM device to evaluate and compare flow patterns and local flow velocity and vorticity in the aneurysm. Results: The experiments revealed no significant change in pressure and flow rate during and after deployment of the MFM device. The flow rate of the incorporated branch was fully preserved. On all models, the aneurysmal flow velocity was significantly reduced. In addition, the device modified local flow patterns, reducing vorticity and better feeding the incorporated branch. Conclusion: This first experimental study provides the basis for a better understanding of the mechanism of the MFM device, which allows intra-aneurysmal flow decrease while preserving incorporated branch and reducing the risk of endoleak type II. The experimental system developed for this study was effective in simulating an endovascular procedure and studying the safety and effectiveness of endovascular devices.