Nonlinear stability of phase transition steady states to a hyperbolic-parabolic system modelling vascular networks
Guangyi Hong, Hongyun Peng, Zhi-An Wang, Changjiang Zhu

TL;DR
This paper investigates the existence and nonlinear stability of phase transition steady states in a hyperbolic-parabolic system modeling vascular network formation, providing rigorous mathematical analysis and stability proofs.
Contribution
It establishes the existence, uniqueness, and nonlinear asymptotic stability of phase transition steady states for a chemotactic aggregation model.
Findings
Existence and uniqueness of steady states proven.
Nonlinear asymptotic stability established.
Methodology includes energy estimates and Hardy-type inequalities.
Abstract
This paper is concerned with the existence and stability of phase transition steady states to a quasi-linear hyperbolic-parabolic system of chemotactic aggregation, which was proposed in \cite{ambrosi2005review, gamba2003percolation} to describe the coherent vascular network formation observed {\it in vitro} experiment. Considering the system in the half line with Dirichlet boundary conditions, we first prove the existence \textcolor{black}{and uniqueness of non-constant phase transition steady states} under some structure conditions on the pressure function. Then we prove that this unique phase transition steady state is nonlinearly asymptotically stable against a small perturbation. We prove our results by the method of energy estimates, the technique of {\it a priori} assumption and a weighted Hardy-type inequality.
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Taxonomy
TopicsMathematical Biology Tumor Growth · MRI in cancer diagnosis · Advanced Mathematical Modeling in Engineering
