Artificial intelligence supported anemia control system (AISACS) to prevent anemia in maintenance hemodialysis patients

TL;DR

This paper introduces AISACS, an AI-based system designed to assist in managing anemia treatment for hemodialysis patients, aiming to improve decision accuracy and reduce costs.

Contribution

The authors developed AISACS, a novel AI system that supports anemia management in hemodialysis patients using data-driven classification techniques.

Findings

AISACS achieved 72-87% correct classification rates.

Clinically appropriate classifications reached 92-98%.

The system effectively supports physician decision-making.

Abstract

Anemia, for which erythropoiesis-stimulating agents (ESAs) and iron supplements (ISs) are used as preventive measures, presents important difficulties for hemodialysis patients. Nevertheless, the number of physicians able to manage such medications appropriately is not keeping pace with the rapid increase of hemodialysis patients. Moreover, the high cost of ESAs imposes heavy burdens on medical insurance systems. An artificial-intelligence-supported anemia control system (AISACS) trained using administration direction data from experienced physicians has been developed by the authors. For the system, appropriate data selection and rectification techniques play important roles. Decision making related to ESAs poses a multi-class classification problem for which a two-step classification technique is introduced. Several validations have demonstrated that AISACS exhibits high performance with correct classification rates of 72-87% and clinically appropriate classification rates of 92-98%.