Negligibility of haptotaxis effect in a chemotaxis-haptotaxis model
Hai-Yang Jin, Tian Xiang

TL;DR
This paper demonstrates that haptotaxis has negligible effects on the boundedness, blow-up, and asymptotic behavior of solutions in a chemotaxis-haptotaxis model, with chemotaxis dominating the dynamics.
Contribution
It shows that the critical mass blow-up phenomenon persists in the combined model and that haptotaxis effects diminish exponentially over time, confirming their negligible impact.
Findings
Critical mass blow-up phenomenon remains in the combined model.
Haptotaxis solution components decay exponentially over time.
Chemotaxis effects dominate the long-term behavior regardless of haptotaxis presence.
Abstract
In this work, we rigorously study chemotaxis effect versus haptotaxis effect on boundedness, blow-up and asymptotical behavior of solutions for a combined chemotaxis-haptotaxis model in 2D settings. It is well-known that the corresponding Keller-Segel chemotaxis-only model possesses a striking feature of critical mass blow-up phenomenon, namely, subcritical mass ensures boundedness, whereas, supercritical mass induces the existence of blow-ups. Herein, we show that this critical mass blow-up phenomenon stays almost the same in the full chemotaxis-haptotaxis model. For negligibility of haptotaxis on asymptotical behavior, we show that any global-in-time haptotaxis solution component vanishes exponentially as time approaches infinity, and the other two solution components converge exponentially to that of chemotaxis-only model in a global sense for suitably large chemo-sensitivity and in…
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Taxonomy
TopicsMathematical Biology Tumor Growth · Slime Mold and Myxomycetes Research · Gene Regulatory Network Analysis
