Photoacoustic microscopical simulation platform for large volumetric imaging using Bessel beam

TL;DR

This paper presents a simulation platform for Bessel-beam photoacoustic microscopy using MATLAB, enabling large volumetric imaging with adjustable depth-of-field through ring slit control, demonstrated on blood vessel models.

Contribution

The authors developed a novel simulation platform that models Bessel-beam photoacoustic microscopy with adjustable depth-of-field, facilitating large-scale volumetric imaging research.

Findings

Successful simulation of blood vessel imaging.

Effective control of Bessel beam depth-of-field.

Platform serves as a research aid for photoacoustic microscopy.

Abstract

We developed a Bessel-beam photoacoustic microscopical simulation platform by using the k-Wave: MATLAB toolbox. The simulation platform uses the ring slit method to generate Bessel beam. By controlling the inner and outer radius of the ring slit, the depth-of-field (DoF) of Bessel beam can be controlled. And the large volumetric image is obtained by point scanning. The simulation experiments on blood vessels was carried out to demonstrate the feasibility of the simulation plat-form. This simulation work can be used as an auxiliary tool for the research of Bessel-beam photoacoustic microscopy.