Experimental development and evaluation of a volume coil with slotted end-rings coil for rat MRI at 7 T

TL;DR

This study presents a novel slotted end-ring volume coil for rat brain MRI at 7 T, demonstrating significant improvements in sensitivity, SNR, and safety over traditional birdcage coils through theoretical, numerical, and experimental validation.

Contribution

The paper introduces a slotted end-ring coil design that enhances MRI sensitivity and reduces noise for small rodent imaging at high magnetic fields, validated by comprehensive simulations and experiments.

Findings

2.22-fold theoretical sensitivity improvement

30% increase in experimental SNR

Fourfold reduction in noise figure

Abstract

A volume coil with squared slots-end ring was developed to attain improved sensitivity for imaging of rat's brain at 7 T. The principles of the high cavity resonator for the low-pass case and the law of Biot-Savart were used to derive a theoretical expression of the coil sensitivity. The slotted-end ring resonator showed a theoretical 2.22-fold improvement over the standard birdcage coil with similar dimensions. Numerical studies were carried out for the electromagnetic fields and specific absorption rates for our coil and a birdcage coil loaded with a saline-filled cylindrical phantom and a digital brain of a rat. An improvement of the signal-to-noise ratio (SNR) can be observed for the slotted volume coil over the birdcage regardless of the load used in the electromagnetic simulations. The specific absorption rate simulations show an important decrement for the digital brain and quite similar values with the saline solution phantom. Phantom and rat's brain images were acquired at 7 T to prove the viability of the coil design. The experimental noise figure of our coil design was four times less than the standard birdcage with similar dimensions, witch showed a 30% increase in experimental SNR. There is remarkable agreement among the theoretical, numerical and experimental sensitivity values, which all demonstrate that the coil performance for MR imaging of small rodents can be improved using slotted end-rings.