Scheduling fixed length quarantines to minimize the total number of fatalities during an epidemic
Yuanyuan Feng, Gautam Iyer, Lei Li

TL;DR
This paper analyzes how to optimally schedule a fixed-length quarantine in an SIR epidemic model to minimize total fatalities, demonstrating that a single contiguous reduction in transmission rate is optimal.
Contribution
It provides a theoretical characterization of the optimal quarantine timing in an SIR model, including an integral condition for the optimal interval.
Findings
Optimal quarantine interval is a single contiguous period.
The integral condition characterizes the optimal timing.
Numerical simulations demonstrate the effectiveness of the approach.
Abstract
We consider a susceptible, infected, removed (SIR) system where the transmission rate may be temporarily reduced for a fixed amount of time. We show that in order to minimize the total number of fatalities, the transmission rate should be reduced on a single contiguous time interval, and we characterize this interval via an integral condition. We conclude with a few numerical simulations showing the actual reduction obtained.
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