Reconstruction of 3D Image of Nanorice Particle from Randomly Oriented Single-Shot Experimental Diffraction Patterns Using Angular Correlation Method

TL;DR

This paper presents a method to reconstruct 3D images of nanorice particles from single-shot diffraction patterns with unknown orientations using angular correlations, advancing imaging techniques with XFEL data.

Contribution

It introduces a novel approach to reconstruct 3D structures from randomly oriented diffraction patterns using angular correlation analysis.

Findings

Successfully reconstructed 3D electron densities of nanorice particles.

Demonstrated the effectiveness of angular correlation method with experimental XFEL data.

Enhanced capabilities for imaging nanostructures with unknown orientations.

Abstract

We reconstructed intensities in Fourier space and electron densities in the real space for an azimuthally symmetric object Nanorice particle (Iron Oxide nanoparticle) exposed in the ultrashort, bright and coherent x-ray free electron laser (XFEL) pulses with random unknown orientations through the method of angular correlations among intensities appeared in ninety eight 2D diffraction patterns collected at Linac Coherent Light Source (LCLS).