Infection fatality ratio of SARS-CoV-2 in Italy
Piero Poletti, Marcello Tirani, Danilo Cereda, Filippo Trentini,, Giorgio Guzzetta, Valentina Marziano, Sabrina Buoro, Simona Riboli, Lucia, Crottogini, Raffaella Piccarreta, Alessandra Piatti, Giacomo Grasselli,, Alessia Melegaro, Maria Gramegna, Marco Ajelli, Stefano Merler
TL;DR
This study estimates the infection fatality ratio of SARS-CoV-2 in Italy at 2.2%, highlighting key risk factors such as age, sex, and comorbidities, based on analysis of close contacts.
Contribution
It provides a precise estimate of IFR for SARS-CoV-2 in Italy and identifies specific risk factors associated with increased mortality.
Findings
Infection fatality ratio of 2.2% in Italy
Male sex and age >70 are significant risk factors
Early infection in the epidemic correlates with higher mortality
Abstract
We analyzed 5,484 close contacts of COVID-19 cases from Italy, all of them tested for SARS-CoV-2 infection. We found an infection fatality ratio of 2.2% (95%CI 1.69-2.81%) and identified male sex, age >70 years, cardiovascular comorbidities, and infection early in the epidemics as risk factors for death.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.