Combining PCR and CT testing for COVID
Chen Shen, Ron Mark, Nolan J. Kagetsu, Anton S. Becker, Yaneer Bar-Yam

TL;DR
This paper demonstrates that combining rapid CT-scan screening with RT-PCR testing significantly reduces COVID-19 transmission and accelerates outbreak extinction compared to using PCR alone.
Contribution
It introduces a combined testing strategy utilizing CT-scans and PCR to enhance COVID-19 containment efforts.
Findings
50-fold reduction in cases after 60 days with combined testing
Effective reproduction rate R(t) decreases by 0.20
Rapid CT-scan screening enables faster isolation and contact tracing
Abstract
We analyze the effect of using a screening CT-scan for evaluation of potential COVID-19 infections in order to isolate and perform contact tracing based upon a viral pneumonia diagnosis. RT-PCR is then used for continued isolation based upon a COVID diagnosis. Both the low false negative rates and rapid results of CT-scans lead to dramatically reduced transmission. The reduction in cases after 60 days with widespread use of CT-scan screening compared to PCR by itself is as high as , and the reduction of effective reproduction rate is . Our results imply that much more rapid extinction of COVID is possible by combining social distancing with CT-scans and contact tracing.
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Taxonomy
TopicsCOVID-19 epidemiological studies · SARS-CoV-2 and COVID-19 Research · COVID-19 diagnosis using AI
