Lung Segmentation from Chest X-rays using Variational Data Imputation
Raghavendra Selvan, Erik B. Dam, Nicki S. Detlefsen, Sofus Rischel,, Kaining Sheng, Mads Nielsen, Akshay Pai

TL;DR
This paper introduces a CNN-based segmentation method that employs a deep generative model to impute missing lung regions in abnormal chest X-rays, aiding automated COVID-19 risk assessment.
Contribution
It presents a novel approach combining data imputation with segmentation to handle high-opacity lung regions in abnormal CXRs.
Findings
Effective segmentation of lungs in abnormal CXRs.
Model generalizes well to cases with extreme abnormalities.
Improved accuracy in automated COVID-19 risk scoring.
Abstract
Pulmonary opacification is the inflammation in the lungs caused by many respiratory ailments, including the novel corona virus disease 2019 (COVID-19). Chest X-rays (CXRs) with such opacifications render regions of lungs imperceptible, making it difficult to perform automated image analysis on them. In this work, we focus on segmenting lungs from such abnormal CXRs as part of a pipeline aimed at automated risk scoring of COVID-19 from CXRs. We treat the high opacity regions as missing data and present a modified CNN-based image segmentation network that utilizes a deep generative model for data imputation. We train this model on normal CXRs with extensive data augmentation and demonstrate the usefulness of this model to extend to cases with extreme abnormalities.
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Taxonomy
TopicsCOVID-19 diagnosis using AI · Radiomics and Machine Learning in Medical Imaging · Lung Cancer Diagnosis and Treatment
