Magnetic Particle Spectroscopy: A Short Review of Applications

TL;DR

Magnetic particle spectroscopy (MPS) is a versatile, sensitive, and cost-effective technique evolving from magnetic particle imaging, with applications in biomedical assays, imaging, hyperthermia, and product tracking.

Contribution

This review summarizes recent applications of MPS, highlighting its development from nanoparticle characterization to diverse biomedical and industrial uses.

Findings

MPS is used for characterizing superparamagnetic nanoparticles.

MPS serves as an independent platform for biomedical assays.

New applications include product tracking and magnetic fingerprinting.

Abstract

Magnetic particle spectroscopy (MPS), also called magnetization response spectroscopy, is a novel measurement tool derived from magnetic particle imaging (MPI). It can be interpreted as a zero-dimensional version of MPI scanner. MPS was primarily designed for characterizing superparamagnetic iron oxide nanoparticles (SPIONs) regarding their applicability for MPI. In recent years, it has evolved into an independent, versatile, highly sensitive, inexpensive platform for biological and biomedical assays, cell labeling and tracking, and blood analysis. MPS has also developed into an auxiliary tool for magnetic imaging and hyperthermia by providing high spatial and temporal mappings of temperature and viscosity. Furthermore, other MPS-based applications are being explored such as magnetic fingerprints for product tracking and identification in supply chains. There are a variety of novel MPS-based applications being reported and demonstrated by many groups. In this short review, we highlighted some of the representative applications based on MPS platform, thereby providing a roadmap of this technology and our insights for researchers in this area.