Complementarity in Complex Networks
Gabriel Budel, Maksim Kitsak

TL;DR
This paper introduces a rigorous mathematical framework for understanding complementarity in complex networks, providing geometric models that improve analysis and understanding of network formation mechanisms.
Contribution
It develops a formal definition and geometric models for complementarity in networks, filling a gap in quantitative methods for these systems.
Findings
Successfully learned geometric representations of real networks
Complementarity frameworks improve network analysis methods
Reveals limitations of similarity-based approaches in networks
Abstract
In many networks, including networks of protein-protein interactions, interdisciplinary collaboration networks, and semantic networks, connections are established between nodes with complementary rather than similar properties. While complementarity is abundant in networks, we lack mathematical intuition and quantitative methods to study complementarity mechanisms in these systems. In this work, we close this gap by providing a rigorous definition of complementarity and developing geometric complementarity frameworks for modeling and inference tasks on networks. We demonstrate the utility of complementarity frameworks by learning geometric representations of several real systems. Complementarity not only offers novel practical analysis methods but also enhances our intuition about formation mechanisms in networks on a broader scale and calls for a careful re-evaluation of existing…
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Taxonomy
TopicsBioinformatics and Genomic Networks · Computational Drug Discovery Methods · Gene Regulatory Network Analysis
