Assessment of the potential of SiPM-based systems for bioluminescence detection
S. Lomazzi, M. Caccia, C. Distasi, M. Dionisi, D. Lim, A., Martemiyanov, L. Nardo, F.A. Ruffinatti, R. Santoro

TL;DR
This paper evaluates the potential of silicon photomultipliers (SiPMs) as a compact, robust alternative to traditional photomultiplier tubes for bioluminescence detection, demonstrating promising initial results.
Contribution
It introduces SiPM-based systems for bioluminescence detection, assessing their performance and proposing feasible implementations as scalable alternatives.
Findings
SiPM systems show comparable sensitivity to photomultiplier tubes.
A proof-of-principle bioluminescence measurement was successfully performed.
Potential for compact, low-cost bioluminescence detectors is demonstrated.
Abstract
Bioluminescence detection requires single-photon sensitivity, extremely low detection limits and wide dynamic range. Such performances were traditionally assured by photomultiplier-tubes based systems. However, development of novel applications and industrialisation call for the introduction of more robust, compact and scalable devices. Silicon photomultipliers were recently put forward as the alternative to phototubes for a new generation of flexible and user friendly instruments. In this article, the figures of merit of a silicon-photomultiplier based system relying on a compact, low cost system are investigated. Possible implementations are proposed and a proof-of-principle bioluminescence measurement is performed.
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