Teaching Design of Experiments using Hasse diagrams
Hans-Michael Kaltenbach

TL;DR
Hasse diagrams serve as an effective visual and analytical tool for designing, understanding, and teaching experimental designs, linking structure, properties, and statistical analysis seamlessly.
Contribution
This paper introduces the use of Hasse diagrams as a central teaching and planning tool for experimental design, simplifying construction and analysis of designs.
Findings
Hasse diagrams enable constructing elementary designs and identifying key properties.
They facilitate defining models and specifying them in statistical software.
Instructors can use diagrams to teach design principles and identify issues like pseudo-replication.
Abstract
Hasse diagrams provide a principled means for visualizing the structure of statistical designs constructed by crossing and nesting of experimental factors. They have long been applied for automated construction of linear models and their associated linear subspaces for complex designs. Here, we argue that they could also provide a central component for planning and teaching introductory or service courses in experimental design. Specifically, we show how Hasse diagrams allow constructing most elementary designs and finding many of their properties, such as degrees of freedom, error strata, experimental units and denominators for F-tests. Linear (mixed) models for analysis directly correspond to the diagrams, which facilitates both defining a model and specifying it in statistical software. We demonstrate how instructors can seamlessly use Hasse diagrams to construct designs by…
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Taxonomy
TopicsStatistical Methods in Clinical Trials · Optimal Experimental Design Methods · Computational Drug Discovery Methods
