IterNet: Retinal Image Segmentation Utilizing Structural Redundancy in Vessel Networks
Liangzhi Li, Manisha Verma, Yuta Nakashima, Hajime Nagahara, Ryo, Kawasaki

TL;DR
IterNet is a deep learning model based on iterative mini-UNets that significantly improves retinal vessel segmentation by leveraging structural redundancy, achieving state-of-the-art results with minimal training data.
Contribution
The paper introduces IterNet, a novel iterative UNet-based architecture that enhances vessel segmentation by exploiting vessel structure and requires only a small labeled dataset.
Findings
Achieves top AUC scores on DRIVE, CHASE-DB1, and STARE datasets.
Can learn effectively from only 10-20 labeled images.
Outperforms existing methods in retinal vessel segmentation.
Abstract
Retinal vessel segmentation is of great interest for diagnosis of retinal vascular diseases. To further improve the performance of vessel segmentation, we propose IterNet, a new model based on UNet, with the ability to find obscured details of the vessel from the segmented vessel image itself, rather than the raw input image. IterNet consists of multiple iterations of a mini-UNet, which can be 4 deeper than the common UNet. IterNet also adopts the weight-sharing and skip-connection features to facilitate training; therefore, even with such a large architecture, IterNet can still learn from merely 1020 labeled images, without pre-training or any prior knowledge. IterNet achieves AUCs of 0.9816, 0.9851, and 0.9881 on three mainstream datasets, namely DRIVE, CHASE-DB1, and STARE, respectively, which currently are the best scores in the literature. The source code is available.
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Taxonomy
TopicsRetinal Imaging and Analysis · Digital Imaging for Blood Diseases · Glaucoma and retinal disorders
