Vitreoscilla sp. hemoglobin (VHb) Expression in Heterologous Hosts: Some Aspects of Their Biotechnological Application
Haitham Qaralleh, Muhamad O. Al-limoun, Khaled M. Khleifat, Khaled Y, Alsharafa, Amjad A. Al Tarawnehc

TL;DR
This paper discusses the biotechnological applications of Vitreoscilla sp. hemoglobin (VHb) expression in various hosts, highlighting its role in enhancing enzyme production, pollutant degradation, and industrial processes by improving oxygen utilization.
Contribution
It provides insights into the mechanisms and potential biotechnological benefits of VHb expression in heterologous hosts, emphasizing its applications in industry and environmental remediation.
Findings
VHb expression can improve enzyme productivity.
VHb helps mitigate toxic conditions like high oxygen levels.
Potential for extending hemoglobin biotechnology to pollutant degradation.
Abstract
It is worth mentioning that the high output of different physiological responses under the expression of vgb, may have a considerable effect on the enzyme productivity, dairy industry, heavy metal uptake, biodegradation of different organic pollutants and other applications. The expression of bacterial haemoglobin is useful in lessening the load of perceived toxic conditions such as high oxygen levels. This in turn probably has the same impact on some peripheral toxic materials. This, hemoglobin biotechnology can be extended to enhance production of pollutants degrading enzymes or production of some valuable manufacturing materials on the case by case bases. It is likely that the mechanism of bacterial hemoglobin (VHb) effects is intermediated via an oxygen trapping action. This may drive the enrichment of ATP production, which is mostly required for higher productivity of needed…
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Taxonomy
TopicsHemoglobin structure and function · Porphyrin Metabolism and Disorders · Erythrocyte Function and Pathophysiology
