Model for growth and morphology of fungal mycelium

TL;DR

This paper introduces a minimal lattice gas model that captures the growth, branching, and morphology of fungal mycelium, providing insights into hyphal dynamics and colony structure through analytical and simulation approaches.

Contribution

The study presents a novel minimal model linking hyphal growth dynamics with colony morphology, validated against experimental data.

Findings

Vesicle distribution along hyphae is exponential.

Hyphal length grows logarithmically over time.

Colony morphology exhibits variability based on model parameters.

Abstract

We present a minimal driven lattice gas model which generates the morphological characteristics associated with single colony mycelium arising from the growth and branching process of fungal hyphae, which is fed by a single source of nutrients. We first analyze the growth and transport process in the primary hypha modeled as a growing 1-d lattice, which is subject to particle (vesicle) loss due to presence of dynamically created branching sites. We show that the spatial profile of vesicles along the growing lattice is an exponential distribution, while the length grows logarithmically with time. We also find that the probability distribution of length of the hypha tends to a Gaussian distribution function at late times. In contrast, the probability distribution function of the time required for growth to a specific length tends to a broad log-normal distribution. We simulate the resultant 2-d morphology generated by the growing primary hypha, quantifying the motility behavior and morphological characteristics of the colony. Analysis of the temporal behavior and morphological characteristics of the resultant 2-d morphology reveals a wide variability of these characteristics which depend on the input parameters which characterize the branching and elongation dynamics of the hyphae. By calibrating the input parameters for our model, we make some quantitative comparison of the predictions of our model with the observed experimental growth characteristics of fungal hyphae and the morphological characteristics of single colony fungal mycelium.