Deep 1D-Convnet for accurate Parkinson disease detection and severity prediction from gait

TL;DR

This paper introduces a deep learning-based gait analysis system using 1D-Convnet for accurate Parkinson's disease detection and severity prediction, achieving state-of-the-art results and aiding clinical diagnosis.

Contribution

It presents a novel 1D-Convnet model that processes gait sensor data for Parkinson's detection and severity prediction, outperforming existing methods.

Findings

Achieved 98.7% accuracy in Parkinson's detection

Achieved 85.3% accuracy in severity prediction

First to predict severity using UPDRS with high accuracy

Abstract

Diagnosing Parkinson's disease is a complex task that requires the evaluation of several motor and non-motor symptoms. During diagnosis, gait abnormalities are among the important symptoms that physicians should consider. However, gait evaluation is challenging and relies on the expertise and subjectivity of clinicians. In this context, the use of an intelligent gait analysis algorithm may assist physicians in order to facilitate the diagnosis process. This paper proposes a novel intelligent Parkinson detection system based on deep learning techniques to analyze gait information. We used 1D convolutional neural network (1D-Convnet) to build a Deep Neural Network (DNN) classifier. The proposed model processes 18 1D-signals coming from foot sensors measuring the vertical ground reaction force (VGRF). The first part of the network consists of 18 parallel 1D-Convnet corresponding to system inputs. The second part is a fully connected network that connects the concatenated outputs of the 1D-Convnets to obtain a final classification. We tested our algorithm in Parkinson's detection and in the prediction of the severity of the disease with the Unified Parkinson's Disease Rating Scale (UPDRS). Our experiments demonstrate the high efficiency of the proposed method in the detection of Parkinson disease based on gait data. The proposed algorithm achieved an accuracy of 98.7 %. To our knowledge, this is the state-of-the-start performance in Parkinson's gait recognition. Furthermore, we achieved an accuracy of 85.3 % in Parkinson's severity prediction. To the best of our knowledge, this is the first algorithm to perform a severity prediction based on the UPDRS. Our results show that the model is able to learn intrinsic characteristics from gait data and to generalize to unseen subjects, which could be helpful in a clinical diagnosis.