Glucose Levels Sensing using Whispering Gallery Modes at mm-Wave Band

TL;DR

This paper presents a low-cost mm-wave sensor based on Whispering Gallery Modes for detecting glucose levels by measuring dielectric property variations in simulated aquatic solutions, demonstrating high sensitivity at specific modes.

Contribution

It introduces a novel integrated WGM-based mm-wave biosensor for glucose detection, combining a dielectric waveguide and resonator with simulation validation.

Findings

High sensitivity of 0.025-0.077 dB/(mg/dL) at specific modes

Effective detection of dielectric property variations in glucose solutions

Simulation results confirm the sensor's potential for non-invasive glucose sensing

Abstract

In this study, an integrated low-cost and complexity mm-wave structure of Whispering Gallery Mode (WGM) is proposed for sensing the glucose levels in mimicking aquatic solutions of concentrations similar to type 2 diabetics. The bio-sensor is composed of a curved dielectric waveguide coupled to a dielectric disc resonator that is loaded with the glucose sample under test. The intense WGM field induced towards the boundary of the DDR is exploited to detect the slight variations in the dielectric properties of different glucose levels via tracing the variations in the magnitude of the transmission coefficient S_{21} in the mm-wave frequency band (49-70 GHz). The WGM resonator shows a high sensitivity performance (0.025-0.077 dB/(mg/dL)) at the lower-order modes WGH_{600} and WGH_{700} as demonstrated by simulations in a 3D full-wave EM solver (Ansys HFSS).