Meaningful causal decompositions in health equity research: definition, identification, and estimation through a weighting framework

TL;DR

This paper develops a framework for causal decomposition in health equity research that explicitly incorporates equity considerations through allowable covariates, providing new estimators for analyzing disparities.

Contribution

It introduces a generalized weighting framework for causal decomposition that respects equity judgments by defining allowable covariates and adapts estimators accordingly.

Findings

Provides weighting-based estimators for causal decomposition respecting equity choices

Generalizes decomposition formulae to include allowable covariates

Discusses conditions under which estimators simplify to existing methods

Abstract

Causal decomposition analyses can help build the evidence base for interventions that address health disparities (inequities). They ask how disparities in outcomes may change under hypothetical intervention. Through study design and assumptions, they can rule out alternate explanations such as confounding, selection-bias, and measurement error, thereby identifying potential targets for intervention. Unfortunately, the literature on causal decomposition analysis and related methods have largely ignored equity concerns that actual interventionists would respect, limiting their relevance and practical value. This paper addresses these concerns by explicitly considering what covariates the outcome disparity and hypothetical intervention adjust for (so-called allowable covariates) and the equity value judgements these choices convey, drawing from the bioethics, biostatistics, epidemiology, and health services research literatures. From this discussion, we generalize decomposition estimands and formulae to incorporate allowable covariate sets, to reflect equity choices, while still allowing for adjustment of non-allowable covariates needed to satisfy causal assumptions. For these general formulae, we provide weighting-based estimators based on adaptations of ratio-of-mediator-probability and inverse-odds-ratio weighting. We discuss when these estimators reduce to already used estimators under certain equity value judgements, and a novel adaptation under other judgements.